Revista Nutrición Continua (RNC) ISSN: 3122-363X | DOI: doi.org/10.70983/rnc240607 Frequency: Semiannual (January–June / July–December) Publication Model: Diamond Open Access Revista Nutrición Continua is the official scientific publication of the Centro de Investigación y Nutrición Continua (CINC), founded in 2025 as a strategic platform for knowledge mobilization and multidisciplinary collaboration within the health sector. Under the institutional backing of CINC, our journal integrates researchers and professionals from various fields who converge in the advanced study of nutrition, reflecting a scientific synergy oriented towards excellence and innovation. Our primary objective is to disseminate cutting-edge scientific production generated by local, national, and international research groups. Revista Nutrición Continua specializes in critical areas such as clinical nutrition, basic and applied science, and precision medicine, acting as a technical bridge between scientific evidence and its practical application for the benefit of society. To ensure integrity and academic rigor, all manuscripts undergo a double-blind peer-review process. Furthermore, we reaffirm our commitment to the democratization of science through our Diamond Open Access Policy, ensuring that knowledge is accessible without Article Processing Charges (APCs) for authors or paywalls for readers. We invite the global academic community to consult our index and contribute high-impact research that transforms nutritional reality through an evidence-based perspective.
Centro de Investigación y Nutrición Continua
Copyright (c) 2026 Dr. Uriel Alberto Angulo Zamudio (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Clinical applications, limitations and prognostic value of electrical bioimpedance analysis in critically ill patients: A narrative review
Critically ill patients experience marked changes in body composition, making monitoring essential. This narrative review summarizes the literature on the clinical applications, limitations, and prognostic value of bioelectrical impedance analysis (BIA) in intensive care. A systematic search of PubMed, the Cochrane Library, and Google Scholar was conducted using MeSH terms and keywords related to BIA, body composition, nutritional status, and critical illness. Scientific articles and book chapters relevant to the research subtopics were selected. Due to fluid resuscitation, traditional BIA predictive equations overestimate fat-free mass. Current evidence supports using overhydration adjustment models and prioritazing direct cellular parameters, such as vector analysis and phase angle (PA). PA is a useful surrogate biomarker for detecting impaired cellular integrity and muscle loss. Longitudinal monitoring of PA has high prognostic value: a decreased PA predicts higher mortality, prolonged ventilation, and neuromuscular sequelae of post-ICU syndrome (ICU-acquired weakness and post-extubation dysphagia). When interpreted with methodological rigor, BIA identifies overhydration, stratifies the risk of complications, and reliably assesses body fluid reserves. After discharge from the ICU, an objective assessment of long-term recovery is possible.
Copyright (c) 2026 Juan Ramón Ballesteros-Villascan , Luis Fernando Cruz-Hernandez , Marycarmen Godínez-Victoria, Nadia Carolina Rodríguez-Moguel, Alan García-Grimaldo (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Intake of vitamins A, C and D and anthropometric status of dyspeptic and gastric cancer patients, Hospital Clínica Bíblica, Costa Rica (2021-2023)
Introduction: Vitamins A, C and D have protective effects against precancerous lesions. We analyzed the intake of vitamins A, C and D and anthropometry in dyspeptic and gastric cancer (GC) patients who attended the gastroenterology service of the Hospital Clínica Bíblica between 2021 and 2023. Methods: Data were collected with an interview and two 24-hour reminders. Results: The sample consisted of 31 people over 18 years of age, mainly with chronic atrophic gastritis and metaplasia, overweight and hereditary and family medical history of gastric lesions. 29% of the sample was diagnosed with H. pylori. Vitamin A and C intakes were adequate, but vitamin D intake was lower than the recommendation. Participants without excess weight had higher mean intakes of vitamin A, C and D than their counterpart, with no significant differences (p=0,24, p=0,44, p=0,72). Participants with autoimmune gastritis and CG had the lowest average intakes, with significant difference for vitamin D (p=0,04). Conclusion: There were no significant differences in vitamin intake according to anthropometry or clinic, except for vitamin D. Given the sample size, these results should be taken with caution.
Copyright (c) 2026 Sofia Villegas-Solís, Sophia Gamboa Lépiz, Christian Campos Núñez, Jose Antonio Moreno Araya, Vanessa Ramírez Mayorga (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Beetroot (Beta vulgaris L.) and digestive health: evidence for its effect on constipation.
ntroduction: Constipation is a common intestinal disorder that impacts people of all ages, affecting their well-being and quality of life. Given the need to find accessible and less invasive therapeutic alternatives, beetroot (Beta vulgaris L.) stands out as a promising option due to its high content of dietary fiber and bioactive compounds. Methodology: A narrative literature review was conducted, focusing on studies addressing the therapeutic potential of beetroot in digestive health and its possible role in the management of constipation. The literature search was performed during the first half of 2026 using the electronic databases PubMed, Scopus, SciELO, and Google Scholar. Results: The findings compiled in this narrative review support the therapeutic potential of beetroot as a functional alternative in the management of constipation. Its richness in dietary fiber and bioactive compounds such as betalains, polyphenols, and caffeic acid contributes to improving intestinal motility, preserving the integrity of the colonic mucosa, and reducing inflammatory markers associated with digestive disorders. Furthermore, its mild laxative effect and ability to modulate the intestinal microbiota are notable, reinforcing its usefulness as a non-invasive dietary supplement. Conclusion: Although preclinical and observational studies offer promising results, more clinical evidence in humans is needed to consolidate its efficacy and establish precise recommendations regarding dosage, method of consumption, and duration of treatment
Copyright (c) 2026 Hector Enrique Fabela Illescas, Estefanía Ramos Gutiérrez, Jimena Aldrete Montiel, Gabriel Betanzos Cabrera (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Dietary Antioxidants and Their Impact on Oxidative Stress and Hypertension: Evidence and Mechanisms Via Endothelial Function
Introduction: Hypertension is a major public health problem closely associated with oxidative stress and endothelial dysfunction. Dietary antioxidants may contribute to blood pressure control. The aim of this narrative review was to synthesize the available evidence on the impact of food-derived antioxidants on oxidative stress, endothelial function, and hypertension. Method: A narrative review of the scientific literature was conducted on antioxidant vitamins, carotenoids, polyphenols, antioxidant-rich foods and dietary patterns, as well as their mechanisms of action and effects on oxidative biomarkers and blood pressure. Results: The reviewed evidence indicates that antioxidants such as polyphenols, carotenoids, and vitamins C and E may improve nitric oxide bioavailability, reduce reactive oxygen species, and modulate pathways related to NADPH oxidase, eNOS, endothelin-1, and the renin-angiotensin system. Antioxidant-rich foods and dietary patterns showed more consistent effects than isolated supplements. However, blood pressure outcomes were variable and generally modest. Conclusion: Food-derived antioxidants may serve as adjuvants in hypertension management, particularly when consumed as part of healthy dietary patterns. Nevertheless, better standardized clinical studies are needed to confirm their clinical relevance.
Copyright (c) 2026 Cesar Antonio Sanchez Cardenas, Lorenzo Hernández Olivas, Daniela Canizales Arce (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Clinical evidence on the immunomodulatory effects of mushroom-derived bioactive compounds in humans: a scoping review
Introduction: Edible and medicinal mushrooms have traditionally been consumed for their health-promoting properties, particularly their capacity to influence immune function. In recent decades, their incorporation into nutraceutical products and dietary supplements has expanded alongside growing scientific interest in mushroom-derived bioactive compounds. However, human clinical evidence remains heterogeneous regarding species studied, extract characterization, populations, and immunological endpoints assessed. A structured synthesis focused on quantitative immune outcomes was therefore needed to clarify the scope and methodological patterns of existing studies. Methods: A scoping review was conducted in accordance with PRISMA-ScR guidelines. PubMed, Scopus, SciELO, and LILACS were searched from inception through March 10, 2025. Eligible studies were primary human clinical investigations evaluating immunomodulatory effects of single-species mushroom interventions administered orally and assessed using predefined quantitative techniques. Studies involving mixed formulations, unidentified species, animal or in vitro designs, or lacking quantitative immunological methods were excluded. Data were charted independently by two reviewers and synthesized narratively using descriptive frequency analysis. Results: Thirty-three studies met inclusion criteria. Although nineteen genera were predefined, only eight were represented in eligible trials. Ganoderma and Pleurotus were most frequently investigated. Polysaccharides and glycoconjugates were the predominant bioactive category. Cancer patients comprised the largest subgroup. Cellular immunity was most commonly assessed. Immunostimulatory effects predominated, alongside anti-inflammatory and bidirectional responses. Conclusions: Mushroom-derived dietary interventions are associated with measurable immune modulation in humans, especially within cellular immunity and inflammatory pathways. Greater extract standardization and harmonized immune biomarkers are required to strengthen translational relevance in clinical nutrition.
Copyright (c) 2026 Valentina Zapata-Cardona, Maria Camila Loaiza-Ceballos, Diana Maryory Gómez-Gallego (Autor/a) https://creativecommons.org/licenses/by-nc/4.0
Copyright (c) 2026 Autor https://creativecommons.org/licenses/by-nc/4.0/
Introduction: The immune system is a network composed of various cells and molecules that respond collectively against exogenous and endogenous antigens. Currently, infectious diseases remain a public health problem, primarily affecting immunocompromised populations, including infants. Therefore, strengthening the immune system through proper nutrition is crucial. The objective of this work is to review foods with immunomodulatory potential, describing their nutrients and bioactive compounds, and presenting examples of foods that contain them, demonstrating the importance of incorporating them into the diet at an early age. Results: The function of various nutrients, such as vitamins and minerals, omega-3 fatty acids, and glutamine, as well as phenolic compounds, in the immune system was described. The role of probiotics in gut immunity was also highlighted, relating the gut microbiota to an essential component of the immune system. Foods such as onions, garlic, apples, papayas, and other common fruits and vegetables in the country were presented. Conclusions: Micronutrients and bioactive compounds can modulate the immune system. Adequate nutrition is essential for the proper development of the immune system and is crucial in childhood, when the immune system is still developing.
Impact of genetic variants on the development of obesity and clinical complications
Introduction: Obesity is a multifactorial disease characterized by abnormal growth of adipose tissue and chronic low-grade inflammation state, associated with multiple metabolic alterations. In addition to environmental factors, several single nucleotide variants (SNVs) in genes encoding cytokines, adipokines, and chemokines have been linked to maintenance of the inflammatory state and development of obesity-related clinical complications. Results: Variants in genes such as NLRP3, IL-1β, IL-6, CCL2, TNF-α, and GPX1 have been associated with increased production of pro-inflammatory cytokines and oxidative stress, promoting insulin resistance, and increasing the risk of obesity. Likewise, genetic variants in ACTN3, ADIPOQ, LEPR, and IRS1 influence the regulation of lipid and glucose metabolism, increasing the risk to dyslipidemia, adiposity, cardiovascular disease, and metabolic syndrome. These findings support a comprehensive clinical approach that considers genetics, inflammation, and adipose tissue function for the management of obesity. Conclusion: Obesity remains one of the major public health challenges worldwide, recognized as a complex disease influenced by genetic, metabolic, environmental, and psychological factors. A multidisciplinary approach and the study of genetic variants enable the identification of predisposition markers that support the development of personalized prevention and treatment strategies. However, healthcare is a personal and collective responsibility that involves adopting healthy lifestyle habits and promoting comprehensive care for physical and mental well-being to prevent and avoid the development of this disease.
Copyright (c) 2026 Autor https://creativecommons.org/licenses/by-nc/4.0//by-nc-sa/4.0
Design of nutrigenetic portfolios targeting CETP and LPL variants in the prevention of dyslipidemias.
Introduction: Nutrigenetics enables the identification of genetic factors that modulate individual responses to dietary components, supporting the development of personalized nutritional strategies for the prevention and management of chronic diseases. Among these factors, genetic variants in CETP and LPL have been linked to an increased susceptibility to dyslipidemias. Designing nutrigenetic portfolios—dietary recommendations tailored to a person’s genetic profile—offers a promising approach to optimize metabolic health. Results: Evidence shows that carriers of the C allele in LPL may experience reductions in triglyceride levels when following diets rich in monounsaturated fats. In contrast, CETP variants, particularly the T (B2) allele, display significant interactions with the intake of simple carbohydrates and monounsaturated fats, influencing HDL cholesterol and triglyceride concentrations. Based on these findings, specific nutrigenetic recommendations include reducing monounsaturated fat intake and limiting sucrose consumption in individuals carrying risk variants in CETP (T allele) and LPL (T allele). Conclusions: Integrating genetic information into dietary planning can substantially enhance the prevention and treatment of dyslipidemias and cardiovascular diseases, reinforcing the value of personalized nutrition in clinical practice.
Copyright (c) 2026 Revista Nutricion Continua https://creativecommons.org/licenses/by-nc-sa/4.0
The Inflammatory Potential of Diet and Mental Health in Adult Women from Sinaloa: An Analysis of Specific Components of the Dietary Inflammatory Index
Introduction: Diet can modulate systemic inflammation, a factor implicated in mental health. The Dietary Inflammatory Index (DII) quantifies this potential. The objective was to evaluate the correlation between the DII (global and components) and mental health in Mexican women. Methods: A pilot, analytical, cross-sectional study was conducted with 34 women (18–45 years) from Culiacán, Sinaloa. Diet was assessed using three 24-hour recalls to calculate the DII. Mental health was measured using the DASS-21 scale. Correlations were determined using the Spearman correlation coefficient. Results: The sample's diet was markedly pro-inflammatory (Median global DII: +4.1; Interquartile range: 3.4–4.7). No significant correlation was found between the global DII and depression, anxiety, or stress scores (p > 0.05). Specific component analysis showed that the pro-inflammatory DII score for omega-6 fatty acids correlated with higher anxiety (r = 0.611; p = 0.0001), and the DII score for trans fats correlated positively with greater depression (r = 0.372; p = 0.030). A positive DII score for omega-3 fatty acids (indicative of deficiency) correlated with higher anxiety (r = 0.425; p = 0.012). Conclusion: In this sample with a pro-inflammatory baseline diet, the global DII was not a predictor of mental health. However, a fatty acid imbalance (high omega-6, high trans, and low omega-3) correlated significantly with greater symptoms of anxiety and stress. These preliminary findings suggest that the type and balance of dietary lipids may be modulators of mental health.
Creatina como Estrategia Ergogénica en el Rendimiento del Voleibol Femenino: Revisión Narrativa
Introducción. La creatina es uno de los suplementos ergogénicos más estudiados y con mayor respaldo científico en el ámbito del rendimiento deportivo. Su papel en el sistema fosfágeno (PCr–ATP) permite mantener la homeostasis energética muscular durante esfuerzos breves y de alta intensidad, favoreciendo la resíntesis de ATP, el aumento de la potencia, la fuerza y la recuperación entre esfuerzos repetidos. El objetivo de este trabajo es analizar críticamente la evidencia científica sobre la suplementación con creatina, abordando desde sus fundamentos bioquímicos hasta su aplicabilidad en distintas disciplinas, con énfasis en su efecto sobre el rendimiento anaeróbico y los vacíos de investigación en mujeres y en el voleibol. Se realizó una revisión narrativa de estudios experimentales, revisiones y metaanálisis publicados entre 2000 y 2025 en las bases de datos PubMed, Scopus, Web of Science, MDPI y SpringerLink. Se incluyeron investigaciones que evaluaron la suplementación con creatina monohidrato en deportistas, considerando su impacto en la fuerza, la potencia, la capacidad de salto y la recuperación muscular. Los resultados muestran que la suplementación con creatina incrementa las reservas musculares de fosfocreatina entre un 20 y un 40%, acelerando la resíntesis de ATP y mejorando el rendimiento en ejercicios intermitentes de alta intensidad. Los efectos positivos son consistentes en deportes como fútbol, baloncesto, atletismo de velocidad y balonmano. En cambio, los estudios en mujeres y en voleibol son escasos y metodológicamente heterogéneos; sin embargo, sugieren mejoras en la altura del salto y la resistencia a la fatiga. En conclusión, la creatina es un suplemento seguro y eficaz para optimizar el rendimiento anaeróbico, aunque se requiere fortalecer la evidencia científica en poblaciones femeninas y específicas por disciplina.
Prevalence of Risky Eating Behaviors in National Team Taekwondo Athletes from Mexico, Central America, and the Caribbean
Objective: To evaluate the prevalence of risky eating behaviors (REB) and possible eating disorders (ED) in national selected taekwondo athletes from Mexico, Central America and the Caribbean Material and methods: A cross-sectional, analytical study was conducted on 72 athletes (38 women, 34 men; mean age 22.7 years) from 11 national teams during a qualifying championship. The Eating Attitudes Test (EAT-26) questionnaire was administered, and questions about compensatory behaviors were asked. Weight and Body Mass Index (BMI) were assessed during habitual and competition periods. An EAT-26 score ≥20, any reported REB, or a BMI <18.0 kg/m² during competition was considered as a "Possible ED". Wilcoxon, McNemar-Bowker, and Mann-Whitney U tests were used for statistical analysis (p<0.05). Results: A reduction in BMI was observed during the competition period (21.2 vs. 20.3 kg/m²; p<0.0001). The prevalence of a possible ED was 91.7% (95% CI: 82.7–96.9), with self-induced vomiting (76.4%) and binge eating (63.9%) the main risk behaviors. On the contrary, the EAT-26 scores showed that only 18.1% reached the risk threshold (≥20). More men (64.7%) than women (26.3%) reported a history of treatment for an ED (p=0.0018). Conclusions: There is a high and normalized prevalence of REB in nationally selected taekwondo athletes from Mexico, Central America and the Caribbean. The discrepancy between behaviors and cognitive attitudes suggests that REB are seen as effective tools for weight control, underestimating their risk to physical and mental health.
La Nutrición como Pilar de la Salud Global en el Siglo XXI
Copyright (c) 2025 Revista Nutricion Continua https://creativecommons.org/licenses/by-nc-sa/4.0
Recomposición corporal: Revisión de estrategias nutricionales, entrenamiento de fuerza y métodos de evaluación
Introducción: La recomposición corporal, definida como la pérdida de masa grasa acompañada del mantenimiento o ganancia de masa muscular, ha cobrado relevancia como enfoque terapéutico y de rendimiento. A diferencia de la simple reducción de peso corporal, este proceso mejora la salud metabólica, la funcionalidad y la composición física. La literatura reciente ha demostrado que la recomposición es posible incluso bajo restricción calórica moderada, siempre que se combinen intervenciones nutricionales y entrenamiento de fuerza con una evaluación precisa. Metodología: Se llevó a cabo una revisión narrativa de la literatura publicada entre 2016 y 2025, centrada en sujetos físicamente activos. Se seleccionaron estudios que abordaran tres ejes principales: ingesta proteica, entrenamiento de fuerza y métodos de evaluación de la composición corporal. Las fuentes se obtuvieron de bases como PubMed, Scopus y Google Scholar, priorizando artículos revisados por pares que emplearan herramientas como DXA, BIA multifrecuencia o antropometría certificada ISAK. Conclusión: Una ingesta proteica entre 1.6 y 2.2 g/kg/día, combinada con entrenamiento de fuerza progresivo, se asocia consistentemente con mejoras en la composición corporal. Aunque el DXA sigue siendo el estándar de referencia, la antropometría ISAK y la BIA multifrecuencia representan alternativas válidas si se aplican bajo estándares técnicos. La integración de nutrición individualizada, estímulo de fuerza y evaluación profesional permite una intervención efectiva y basada en evidencia para optimizar la recomposición corporal en contextos deportivos y clínicos.
Association between body composition, nutritional parameters, and capillary blood glucose in young adults
Introduction: Obesity is a major risk factor for the development of type 2 diabetes mellitus, partly due to the imbalance between fat mass and lean mass, which negatively affects glucose regulation, insulin sensitivity, and inflammatory status. This study aimed to analyze the association between body composition, dietary intake, and capillary glucose levels in young adults from Culiacan, Sinaloa, Mexico. Methods: A total of 27 young adults (mean age 27.63 ± 8.48 years) were included. Anthropometric variables, body composition by bioelectrical impedance, fasting capillary glucose levels (8–10 h), and dietary intake via a 24-hour dietary recall were assessed. Participants were classified into two groups according to their glucose levels: normoglycemia (<100 mg/dL) and hyperglycemia (≥100 mg/dL). Results: Participants in the hyperglycemic group showed a higher percentage of body fat, lower muscle mass, and lower intake of vitamins B6 and E compared to those in the normoglycemic group. Significant correlations were found between capillary glucose levels and body fat percentage (r = 0.483, p = 0.014), muscle mass (r = -0.475, p = 0.016), total body water (r = -0.505, p = 0.010), hip circumference (r = 0.483, p = 0.014), vitamin B6 intake (r = -0.444, p = 0.017), and vitamin E intake (r = -0.345, p = 0.044). Conclusion: Higher body fat percentage, lower muscle mass, and inadequate intake of vitamins B6 and E are associated with elevated capillary glucose levels. Promoting healthy body composition and micronutrient-rich diets may play a key role in the early prevention of metabolic disturbances.
Association between anemia in pregnant adolescents and neonatal birth weight in a secondary-level hospital in Mexico.
Introduction: Anemia during pregnancy is a risk factor for adverse perinatal outcomes, especially among adolescents, a group facing greater biological and social vulnerabilities. This study aimed to assess the association between third-trimester maternal anemia and neonatal birth weight in a sample of pregnant adolescents in Mexico. Method: A cross-sectional, retrospective, and analytical study was conducted through a review of clinical records from a secondary-level public hospital in Culiacán, Sinaloa. Adolescents (≤19 years) with full-term deliveries between January and April 2023 were included. Anemia was defined as hemoglobin <11 g/dL. Neonatal outcomes were compared between mothers with and without anemia, and the relationship between maternal hemoglobin and birth weight was analyzed. Results: A total of 276 pregnant adolescents were analyzed. The prevalence of anemia was 28.98%. The mean birth weight was significantly lower in neonates born to mothers with anemia compared to those without (3,254 g vs. 3,353 g; p = 0.0397), although no association was found with low birth weight (<2,500 g; p > 0.05). No significant correlation was found between maternal hemoglobin levels and neonatal weight. Adolescents aged 13–16 years had a higher risk of anemia compared to those aged 17–19 years (OR: 3.234; p < 0.001). Conclusion: Anemia in pregnant adolescents was associated with a significant reduction in mean neonatal birth weight, without increasing the proportion of low birth weight. These findings highlight the need to strengthen screening and timely treatment of anemia during adolescent pregnancy to prevent adverse neonatal outcomes.
Nutrition and Epigenetics: Nutrient-influenced epigenetic modifications and their impact on health and disease development.
Introduction: Epigenetics investigates heritable modifications that regulate gene expression without altering DNA, such as methylation, histone modifications, and non-coding RNA. Factors like diet influence these mechanisms and impact chronic disease risk. This article aims to provide an updated overview of the effect of specific nutrients on epigenetic mechanisms and their relationship with pathologies like cancer, diabetes, and neurodegenerative disorders. Understanding this interaction will enable the design of preventive and therapeutic nutritional strategies. Results: Nutrients such as folic acid, methionine, choline, vitamin B12, polyphenols, and omega-3s modulate epigenetic processes. C1 metabolism, mediated by folates, is critical for synthesizing methyl groups essential for DNA methylation; its deficiency is linked to hypomethylation, neural tube defects, and metabolic dysregulation. Methionine regulates the production of S-adenosylmethionine (SAM), which is associated with genomic stability, and its moderate restriction reduces tumor growth. Bioactive compounds (polyphenols, omega-3s) inhibit enzymes like DNMT and HDAC, regulate microRNA, and activate sirtuins (e.g., resveratrol), promoting protective gene expression. The interaction between choline and gut microbiota also influences the gut-brain axis and neuropsychiatric disorders. Conclusions: Nutrition influences epigenetic mechanisms, modulating gene expression and affecting chronic disease risk (e.g., cancer, diabetes). Nutrients and bioactive compounds in balanced diets promote epigenetic health. Personalized nutrition, integrating basic and clinical research with sustainable, multidisciplinary strategies, optimizes interventions tailored to individual needs.
Nutritional intervention in a patient with oncological treatment for breast cancer after metabolic surgery
Introduction: Obesity affects cancer prognosis in all aspects. It has been observed that patients with breast cancer and excess adipose tissue have larger primary tumors and higher rates of lymphatic invasion compared to patients of healthy weight. The most effective alternative for sustained weight loss is metabolic surgery, which has recently been of great interest in the field of cancer. However, to date, the effect on patients undergoing metabolic surgery and who have been diagnosed with cancer a few months after surgery is unknown; therefore, the appropriate nutritional approach and the consequences on the patient's body are unknown.Methodology: A 45-year-old female patient underwent metabolic surgery of the gastric sleeve type 6 months after being diagnosed with stage II-A breast cancer. She attended nutritional consultations every 15 days, during a period of 9 months in which anthropometric data, a questionnaire on symptoms and body composition analysis were obtained. Results: During the intervention period, the relevant changes were made to the nutritional treatment, with respect to tolerance and symptoms. At the end of the treatment, the patient had a reduction of 19.1 kg compared to her initial weight. She reached a BMI of 26.9 kg/m2, which changed her diagnosis from type II obesity to overweight. The loss of MME was only 1.2 kg of the initial muscle and with the nutritional treatment the symptoms associated with the chemotherapy were considerably reduced. Conclusions: It will be observed that the nutritional intervention promptly decreases the appearance of adverse effects after oncological treatments and promotes the maintenance of skeletal muscle mass, even after metabolic surgery. In addition, the decrease in adipose tissue and the points previously mentioned improve the prognosis in patients with breast cancer.
Copyright (c) 2025 Nutrición Continua https://creativecommons.org/licenses/by-nc-sa/4.0
The role of omics sciences in precision nutrition
Introduction: Precision nutrition emerges as an innovative approach that adapts dietary interventions to the biological, genetic, and environmental diversity of each individual. Unlike traditional recommendations, this paradigm seeks to optimize the prevention and management of chronic diseases through personalized strategies. Omics sciences, such as nutrigenetics, nutrigenomics and nutriepigenetics, play an essential role in understanding the interactions between genes, nutrients and the environment, allowing for more effective and individualized interventions. Results: Nutrigenetics explores how genetic variants influence metabolic response. Prominent examples include the rs628031 polymorphism in SLC22A1/OCT1, related to response to drug treatments, and rs174547 in FADS1, involved in omega-3 synthesis. On the other hand, nutrigenomics analyzes how nutrients modulate gene expression, highlighting the positive impact of omega-3 fatty acids and Mediterranean diets in the regulation of inflammatory and antioxidant genes. Nutriepigenetics complements this approach by studying how diet affects gene expression through mechanisms such as DNA methylation. Conclusion: These advances highlight the potential of food and exercise in molecular regulation, promoting a comprehensive and personalized approach to health. However, the implementation of precision nutrition faces challenges such as high costs and the need for advanced infrastructure. Nevertheless, this discipline promises more inclusive, sustainable and effective interventions, with the potential to transform global health and reduce inequalities.